Desorption and adsorption of molecular motors on actin filaments co-operation of the transport density.docVIP

 PAGE \* MERGEFORMAT 12 Desorption and adsorption of molecular motors on actin filaments co-operation of the transport density [Abstract] Objective To investigate the desorption and adsorption of actin on the one-dimensional density distribution of molecular motor transport cooperation. Methods used open boundary conditions one-dimensional asymmetric simple exclusion process completely (TASEP) to describe the molecular motor in the microfilament cooperation on transport, and adopted by Monte Carlo computer simulation of the desorption and adsorption of molecular motor on its probability density distribution. The results when the filaments do not exist on the molecular motor desorption and adsorption phenomena, the density of actin distribution in the density of stable phase 2; and when there are large actin desorption and adsorption probability, the density distribution of filaments is only one kind of density is stable. Conclusion microfilament density distribution on the phase diagram depends on the desorption and molecular motors The size of the adsorption probability. [Key Words] molecular motors; desorption and adsorption; co-transport; density distribution Abstract: Obejective To investigate the effects of the phenomenon of desorption / adsorption on the density profiles of the cooperative transport by molecular motors on one-dimensional microfilaments. Methods One dimensional totally asymmetric simple exclusion processes (TASEP) with open boundary were taken to describe the molecular motors’cooperative transport on the microfilament. And the effects of molecular motors’ detachment and attachment rate to the density profiles were studied by using Monte Carlo computer simulation experiments. Results In the absence of desorption or adsorption by molecular motors, two steady phases were observed in the density profiles on the microfilaments, whereas in the presence of a large value of desorption / adsorption probability (D = 10), there was only one