Determination of intestinal particles in Thailand oleanolic acid.docVIP

 PAGE \* MERGEFORMAT 7 Determination of intestinal particles in Thailand oleanolic acid Study: Pine million THE ACADEMY, Huang Yiping [Abstract] Objective To establish intestinal particles in Thailand Determination of oleanolic acid. Methods using high performance liquid chromatography method with Kromasil KR100-C18 column (4.6 mm 250 mm, 5 m) as the separation column, methanol: water: Glacial acetic acid: triethylamine (85: 15:0.04:0.02) as mobile phase, detection wavelength was 220 nm. Results of oleanolic acid in the sample size in the range of 2.04 ~ 10.2g good linear relationship, the correlation coefficient was 0.999 2 The average recovery was 98.60%, RSD = 1.76%. Conclusion The method is reliable, simple and feasible, to control the quality of Changtai particles provide a scientific basis. [Keywords:] Changtai particles, oleanolic acid, HPLC Abstract: ObjectiveTo develop a method for determination of oleanolic acid in Changtai Granule. MethodsHPLC was carried out on a KR100-C18 (4. 6 mm 250 mm, 5 m) using MeOH-H2O-HOAc-TEA (85: 15:0 . 04: 0. 02) as the mobile phase, and the detection wavelength 220nm. ResultsThe standard curve was linear in the range of 2.04 ~ 10.2. g. The average recovery and RSD% were 98. 60% and 1.76%. ConclusionThis method is accurate, reliable and provides a scientific index for the quality control of Changtai Granule. Keywords:: Changtai Granule, Oleanolic acid, HPLC Changtai particles Integrative Medicine Hospital of Jiangsu Province, Wang Xiaoning, Director of clinical experience side by diffusa, Chinese herbal medicine Coix Seed flavor composition of 7, for the adjuvant treatment of colorectal cancer, the effect is significant. The preparation of effective oleanolic acid composition with Liver, Liver drug solution, blood glucose and lipids, anti-inflammatory anti-virus, anti-cancer and so on [1], the anticancer effect of oleanolic acid almost throughout all stages of tumor development, including inhibition