Diagnosis of Helicobacter pylori infection in two children Comparison.docVIP

 PAGE \* MERGEFORMAT 7 Diagnosis of Helicobacter pylori infection in two children Comparison [Abstract] Objective To study the 14C-urea breath test (14C-UBT and H. pylori antigen test card (HpSA detection of children with Helicobacter pylori (Hp infection value. Methods 68 cases accepted by endoscopy upper gastrointestinal symptoms 14C-UBT for children and Helicobacter pylori stool antigen test, and gastric juice samples were taken at the same time FQ-PCR detection to FQ-PCR test results as the gold standard, the 14C-UBT and H. pylori antigen test for initial evaluation . 14C-UBT results of the sensitivity, specificity and accuracy were 93.5%, 97.3%, 95.6%, HpSA sensitivity, specificity and accuracy were 87.1% and 100%, 94.1%. Conclusion 14C-UBT method is slightly better than the sensitivity of HpSA law, but HpSA method is simple and easy to promote the use in the laboratory. [Keywords:] Helicobacter pylori antigen Helicobacter pylori (Helicobacter pylori, Hp) and chronic gastritis, peptic ulcer growing emphasis on the relationship, HP infection in children with gastrointestinal inflammation, an important cause of peptic ulcer in this. At present, the diagnosis of Hp infection in non-invasive method of multi- the 14C-UBT as the gold standard, but this method reduces the specificity of young children, and the collection of such problems among the exhaled air [1]. Helicobacter pylori stool antigen (HpSA) is a clinical application in recent years to promote kinds of non-invasive method. In this study, 14C-UBT test, HpSA antigen detection cards and FQ-PCR detection of 14C-UBT test, HpSA antigen detection in patients with Hp infection in children application. 1 Materials and Methods 1.1 study Select 2006-03 ~ 2008-10 in our hospital because of upper gastrointestinal symptoms in pediatric patients received gastroscopy 68 cases (all cases were ruled out taking over 4 weeks of antibiotics, bismuth, H2 blockers and proton pump inhibitor agent drugs, in