DTI imaging in acute canine model of spinal cord injury.docVIP

 PAGE \* MERGEFORMAT 11 DTI imaging in acute canine model of spinal cord injury Of: HE Ji Ma, Ms Wong, Tan Wei, Gao double, Fu Vina [Abstract] Objective MR-DTI imaging of spinal cord injury on acute apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values #8203;#8203;were detected, of MR-DTI imaging in spinal cord injury in the application. canine spinal cord injury model approach. spinal cord injury and spinal cord injury model before the model was successfully carried out 30 min, respectively, FSE and DTI MRI examination (FSET2WI, DTI b = 500 s/mm2, diffusion gradient directions = 15, measured before spinal cord injury after spinal cord ADC values #8203;#8203;and FA values. Results spinal cord injury before the ADC value (0.97 + -0.18) 10-3mm2 / s, FA value of 0.58 + -0.10; ADC value increased after spinal cord injury (1.16 + - 0.16) 10 -3 mm2 / s (t = 1.676, P = 0.07gt; 0.05), FA values #8203;#8203;decreased to 0.34 + -0.06 (t = 4.512, P = 0.002 lt;0.05). Conclusions of acute spinal cord injury in the rise of ADC values High obvious, FA was significantly lower, DTI technology for the diagnosis of acute spinal cord injury provide valuable information. [Keywords:] spinal cord; injury; diffusion tensor imaging Abstract: Objective To observe the apparent diffusion coefficients (ADCs) and fractional anisotropy (FA) value changes of acute injured canine spinal cord with MR diffusion tensor imaging (DTI). Methods The canines’ spinal cord injure model was firstly made. Before and 30 mins after injury, the MRI and DTI were examined (FSET2WI, DTI b = 500 s/mm2), direction of diffusion sensitive gradients being 15. The ADCs and FA value of the spinal cord were calculated. Results The ADCs and FA of normal canine spinal cord were (0.97 + -0.18) 10-3mm2 / s and 0.58 + -0.10 respectively. The ADCs and FA of injured canine spinal cord were (1.16 + -0.16) 10-3mm2 / s (t = 1.676, P = 0.07gt; 0.05) and 0.34 + -0.06 (t = 4.512, P = 0.002 lt;0.