Drinking game of the brain stem lesion cerebral ischemia-reperfusion injury in rats.docVIP

 PAGE \* MERGEFORMAT 20 Drinking game of the brain stem lesion cerebral ischemia-reperfusion injury in rats 【Abstract】 Objective To observe the brain stem to drink on focal cerebral ischemia-reperfusion brain injury in rats and to further explore its mechanism. Methods The middle cerebral artery embolization in rats produced focal cerebral ischemia-reperfusion injury model. The use of immunohistochemistry, respectively, TTC staining and Zea Longa 5-point scale scoring system to observe the brain stem in brain tissue of treated drinking Bcl  2 protein expression, infarct volume and neurological changes in behavior. Results Compared with model group, treatment group significantly reduced symptoms of neurological impairment (P lt;0.05); infarct volume reduced by about 40%; in each time point Bcl  2 expression in both the high and the model group (P lt;0.05). Conclusion brain stem drinking by Prostisol, Huoxue network of comprehensive control measures can not only increase apoptosis inhibitory gene Bcl  2 expression, reduced infarct volume, but also can improve the symptoms of nerve injury, reducing structural damage brain tissue, lack of brain Blood-reperfusion injury caused significant protection. Keywords: Brain stem drink Bcl  2 protein in ischemia-reperfusion injury Experimental Study of the Protective Effects of Naogengyin on Cerebral Ischemia-reperfusion Injury in Rats Abstract: ObjectiveTo measure the protective effects of Naogengyin on cerebral ischemia  reperfusion injury in rat and its mechanisms.MethodsThe model of focal reperfusion injury after cerebral ischemia in rats was made by middle cerebral artery occlusion. The effect of Naogengyin on expression of Bcl  2 proin, cerebral infarct volume and behavioral change in rats brain tissue were observed by immunohistochemical method, TTC staining and Zea Longa method respectively.ResultsCompared with the control group, neurological grades in Naogengyin group were lower (P