Dopamine dobutamine treatment of neonatal hypoxic ischemic encephalopathy Observation of 137 cases.docVIP

 PAGE \* MERGEFORMAT 4 Dopamine dobutamine treatment of neonatal hypoxic ischemic encephalopathy Observation of 137 cases [Keywords:] neonatal hypoxic ischemic encephalopathy, dopamine, dobutamine Neonatal hypoxic ischemic encephalopathy (HIE is caused by perinatal asphyxia of the most common and serious complication of asphyxia due to reduced oxygen content in blood supply, cerebral hypoperfusion, caused by a range of symptoms, expressed as cyanosis, convulsions, screaming, coma and brain dysfunction, and other changes. In recent years, we applied dopamine and dobutamine treatment of neonatal hypoxic ischemic encephalopathy and achieved good results, are as follows. 1 Clinical data 1.1 General information to February 2002 ~ October 2007 in our hospital 137 cases of hospitalized patients for data, 137 cases of children meet the 1996 Hangzhou Conference established the basis of clinical diagnosis and indexing standards. Randomly divided into two groups, treatment group of 87 patients, male 63, female 24 cases, admission age lt;6 h 27 例, ~ 24 h 48 例, ~ 72 h 12 cases, mild in 23 cases, 51 cases of moderate and severe in 13 cases. control group of 50 patients, 33 males and 17 females, aged admission lt;6 h 18 例, ~ 24 h 28 例, ~ 72 h 4 cases, mild in 17 cases, 26 cases of moderate and severe in 7 cases. The main clinical manifestations: treatment group : 15 cases of disturbance of consciousness, hypotonia in 41 cases, 39 cases before the full fontanelle, convulsions in 15 cases, 9 cases of irregular breathing. control group: 13 cases of disturbance of consciousness, hypotonia in 44 cases, 22 cases before the full fontanelle, convulsions 17 cases, 7 cases of irregular breathing. children by course and main clinical manifestations were statistically comparable (Pgt; 0.05. 1.2 The treatment groups were given comprehensive treatment, including warm, keep the airway open, rational oxygen, control of seizures, reducing intracranial pressure, correct acidosis