Echocardiographic evaluation of valsartan on left ventricular remodeling of hypertension reversal effect.docVIP

 PAGE \* MERGEFORMAT 13 Echocardiographic evaluation of valsartan on left ventricular remodeling of hypertension reversal effect Of: Zhu Jun Jie Tang Lai Tao Dan Small today Liang Yan Yang Yongjian Liao Mingsong [Abstract] Objective To evaluate echocardiography valsartan on left ventricular remodeling in essential hypertension. METHODS 178 patients with essential hypertension application of valsartan 80mg / d oral treatment regimen of 12 months. observed during the treatment of blood pressure and changes in symptoms and signs, respectively, before treatment and every 3 months after treatment by echocardiography in phases cardiac morphological changes observed. Results After two weeks of valsartan in the treatment of blood pressure began to decline, has stabilized after five weeks, the heart chamber diameter, wall thickness and left ventricular mass index after 3 months of treatment began to decrease (P lt;0.05,6 months to 1 year was significantly decreased (P lt;0.01 and trends to stability. Conclusions Valsartan can effectively reverse the result of essential hypertension left ventricular remodeling, echocardiography can be comprehensive and objective quantitative evaluation of cardiac structure and wall motion state. [Keywords:] partition wall motion analysis of full-automatic M-mode echocardiography of left ventricular remodeling of hypertension Valsartan Blood pressure in hypertensive patients can lead to higher long-term sustainability of significant left ventricular remodeling and left ventricular remodeling is not only the incidence of cardiovascular disease and mortality predictor of cardiovascular events is also an independent risk factor, through drug intervention can effective in reversing left ventricular remodeling, can significantly reduce the incidence of cardiovascular events [1]. Valsartan Losartan is a novel class of drugs, through selective antagonism of angiotensin receptor (AT1 and play a role in blood pressure. The application