Escherichia coli resistant integrons and the relationship between horizontal gene transfer research progress_0.docVIP

 PAGE \* MERGEFORMAT 19 Escherichia coli resistant integrons and the relationship between horizontal gene transfer research progress [Keywords:] integron; Escherichia coli; horizontal transfer Integron can capture or removal of specific gene cassette leading mobile gene cassette, but also the nature of the bonding particles, transposons, integrated phage or the bacterial chromosome to move between and through these mobile devices in the same genus and between different species Communication has become an important current cause of extensively drug-resistant Escherichia coli. now antibiotic resistant and multiple drug resistance of bacteria has become a global concern. Escherichia coli (Escherichia coli, E.coli), is present in humans and animals the normal intestinal flora, causing clinical infection is the most common and one of the most important Gram-negative bacteria, from the 70s of last century the emergence of drug resistance reported so far, more severe drug resistance of Escherichia coli. People In the study of mechanisms of resistance showed that the integration is a sub-horizontal gene transfer and drug resistance is closely related to the cloning and expression vectors, the storage and transfer of resistance genes is an important structure of Hall and others In 1991 the official presentation of the integration of gene cassettes son (Gene cassette) system concept. gene cassettes integrated subsystem is a site-specific recombination function with movable components, and the two conserved gene cassette between the composition, and enzyme in the case can be captured and expression of foreign genes, and through the bonding properties of tablets, transposons, integrated phage or the bacterial chromosome in the genus with the species and spread among different species, so widely spread bacterial resistance is the rapid development of multi-drug resistant bacteria of the important reasons . 1 gene cassette integrated subsystems Gene cassette inte