Eucommia leaf extract of chlorogenic acid purification.docVIP

 PAGE \* MERGEFORMAT 10 Eucommia leaf extract of chlorogenic acid purification Authors: Yuan Hua, Deng Liang, Yang Xiaojun, Yan Zhi-guo, WU Yuan-xin Keywords: chlorogenic acid;,, extraction;, and purification;,, Eucommia Leaf Abstract: Objective To study the Eucommia leaf extract of chlorogenic acid purification methods. Methods water extraction, flocculation bleaching, resin adsorption, extraction and purification of re-crystallization process. The results of flooding in Eucommia leaf extracts concentrated with 1% chitosan flocculation to hybrid, activated carbon decolorization get into the sample solution, injection solution with the NKA-9 resin adsorption, 50% ethanol desorption, eluate after concentration Crude methanol recrystallization purity of ≥ 97% are of chlorogenic acid, extraction rate ≥ 65%. Conclusion improved optimization of chlorogenic acid in Eucommia leaf extraction and purification method for Eucommia the full utilization of resources and industrial development to provide a reference. Keywords:: chlorogenic acid; extraction; purification; Eucommia Leaf Study on the Extraction and Purification of Chlorogenic Acid in Eucommia ulmoides Oliv. Leaves Abstract: Objective To study the optimum extraction and purification process for chlorogenic acid in Eucommia ulmoides Oliv. Leaves. MethodsThe process was carried out by water extraction, 1% chitosan flocculation, actived char decolorization, NKA9 resin adsorption, 50% ethanol desorption and methanol recrystallization . ResultsThe extracting ratio of chlorogenic acid was 68% with purity of 97%. ConclusionAn optimum and improved technology for the extraction and purification of chlorogenic acid in Eucommia ulmoides Oliv. Leaves was investigated. It is helpful to industrial production of chlorogenic acid. Keywords:: Chlorogenic acid; Extraction; Purification; Eucommia ulmoides Oliv. Eucommia Eucommia ulmoides Oliv. Is a species endemic to China’s econ