EXD soup cytochrome P450 1A2 efficacy and gene polymorphism analysis of the relationship_0.docVIP

 PAGE \* MERGEFORMAT 14 EXD soup cytochrome P450 1A2 efficacy and gene polymorphism analysis of the relationship Of: Yang Ming, Ding Chunyan, Zhang Xian, Chen via Po, Luyun Tian, #8203;#8203;Tang Bo, Zhu first London, he stars [Abstract] Objective To investigate the treatment of male climacteric syndrome Erxian soup clinical efficacy of individual differences in cytochrome P450 1A2 (CYP1A2) gene single nucleotide polymorphism. Methods 48 cases of renal deficiency of both yin and yang, male menopause comprehensive Treatment of patients with symptoms Erxian 3 months, with symptoms of Istanbul, Bosphorus University, Department of Psychology, quantitative scoring method and with reference to lt;lt;Chinese new drug clinical research guidance Policy “gt;, quantitative deficiency of kidney yin and yang, the two scores, using polymerase chain reaction (PCR ) amplification of CYP1A2 G2964A gene, analysis of the clinical efficacy and Erxian soup CYP1A2 G2964A gene single nucleotide polymorphisms. the treatment group and control group genotype and allele distribution between the no significant difference effective group of 32 subjects, 16 patients of the CYP1A2 G2964A genotype G / G (56.25%), ineffective group of 16 subjects, 11 cases of CYP1A2 G2964A genotype G / A (68.75%). Gene groups before treatment, after the symptoms and signs scores showed no significant difference between the genome of renal deficiency of both yin and yang, master card, plays no significant differences in disease rates. Conclusions Treatment of male climacteric syndrome Erxian individuals with the genotype of CYP1A2 G2964A G / G high efficiency, the individual with CYP1A2 G2964A genotype G / A non-efficient. [Keywords:] Erxian soup, male climacteric syndrome, cytochrome P450 1A2 Tom is a Professor Zhang Bone EXD 20th century, created 50 years of prescription therapy for menopause, after decades of clinical observation, has become the treatment of menopausal syndrome, post-parties [1].