Fixed silk fibroin membrane electrochemical luminescence behavior of ruthenium bipyridine Research and Application.docVIP

 PAGE \* MERGEFORMAT 16 Fixed silk fibroin membrane electrochemical luminescence behavior of ruthenium bipyridine Research and Application Of: Cai Zhuo Li Lijun Wu Qitao Chenglong Jun Hao Koh Lan Xue-chao [Abstract] pyridine ruthenium based diphenhydramine couplet (Ru (bpy) 2 +3) of the ECL and Sensitization of ruthenium bipyridyl silk fibroin composite film modified glassy carbon electrode and good stability, the establishment of a porous films with silk fibroin bipyridyl ruthenium complex modified glassy carbon electrode electrochemical luminescence detection of a new method of diphenhydramine. The results show that the modified electrode has good electrochemical activity and electrochemiluminescence (ECL) response. Under optimum conditions, the concentration of diphenhydramine in the 1.0 × 10-4 ~ 1.0 × 10-7 mol / L range and its relative intensity showed a good linear relationship (r = 0.9989), the detection limit was 2.3 × 10-7 mol / L (S / N = 3. Continuous parallel determination of 3.78 × 10-5 mol / L 5 diphenhydramine, luminous intensity of the RSD is 1.76%. for diphenhydramine in real samples samples with satisfactory results. [Keywords:] diphenhydramine, ECL, bipyridine ruthenium, silk fibroin, chemically modified electrode Abstract Based on the increasing effect of diphenhydramine on Ru (bpy) 32 + electrochemiluminescence (ECL) system, an ECL method was developed for the determination of diphenhydramine hydrochloride by silk fibroin (SF) Ru (bpy) 2 +3 composite film modified glassy carbon electrode. A highly sensitive sensor was prepared based on SF Ru (bpy) 2 +3 composite film modified glass carbon electrode. Its fabrication procedure, related experiment conditions and electrochemical characterization were studied. Under the optimum experimental condition, the linearity of diphenhydramine concentration to ECL intensity was achieved (r2 = 0.9989) in the concentration of diphenhydramine hydrochloride of 1.0 × 10-4-1.0 × 10-7 mol / L and the