Four-dimensional CT images of lung cancer in the MIP integration within the target volume to determine.docVIP

 PAGE \* MERGEFORMAT 29 Four-dimensional CT images of lung cancer in the MIP integration within the target volume to determine Author: He Han, Bao-Yong, Zhang Li, Huang Xiaoyan, Huang Shao-Min, WANG Wei-hua, Liu Yuan, Chen Li, Fan Wei, Chen Ming, Liu Mengzhong, Nian-Ji Cui, DENG Xiao-Wu Abstract [Objective] To verify that the maximum intensity projection (MIP) software to automatically generate the fusion image sketched gross tumor volume (GTV) of reliability. [Method] 20 patients with pathologically confirmed lung cancer patients, according to lesion characteristics of adjacent tissues were divided into A (low-density lesions surrounded by normal lung organizations) and B (lesions around with other organizations close to the density or high density). A physician at the same four-dimensional CT (4D-CT) of the 10-phase, three phase, 2 phase, MIP fusion images outlined GTV (GTV10, GTV3, GTV2, GTVMIP). Observation of GTV displacement of volume change and centers to compare the differences between the four methods. [Results] A group GTV10 and GTV3, GTV2 and GTVMIP ratios were 1.07 ± 0.03,1.10 ± 0.03 and 1.08 ± 0.07; four were the focal point in the X, Y, Z axis, the difference is less than 1mm and no statistical significance (Pgt; 0.05). B group GTV10 and GTV3, GTV2, GTVMIP ratios were 1.10 ± 0.07,1.16 ± 0.09,1.27 ± 0.26; four were the focal point in the X, Y, Z axis, the difference is less than 1mm and no statistical significance (Pgt; 0.05). [Conclusion] For organizations, surrounded by normal pulmonary alveolar lesions in the four-dimensional CT in the MIP image, sketch GTV is reliable, but the lesions close to the organization such as density or high density, when not sufficiently precise, it is recommended replacing three-phase integration images, instead of 10 individual special circumstances phase of the fusion images. Keywords: lung cancer radiation therapy breathing exercise maximum intensity projection Internal Target Volumes