Hand Foot and mouth disease trends.docVIP

 PAGE \* MERGEFORMAT 19 Hand Foot and mouth disease trends Keywords: Hand, Foot and Mouth Disease trends Hand, Foot and Mouth Disease (Hand foot mouth disease, HFMD) is a common intestinal infectious disease caused by a virus, one of the world’s sexually transmitted diseases, most of the world have the disease prevalence reported. The disease, mainly in the 5 years of age infants can cause fever and hand, foot, mouth and other parts of the skin rashes, ulcers. Individual patients, there may be myocarditis, pulmonary edema, aseptic meningitis and other fatal complications. I query the current literature in recent years, will make the following overview of trends in its prevalence. An international fashion trends HFMD since the first report in 1957 in Canada, New Zealand, Seddon be described as early as 1958, Canada Robinson stool and throat swabs from patients in group A Coxsackie virus isolated from 16 (Coxsackie virus A16, Cox A16), while serum fourfold increase in antibodies, preliminary investigations Cox A16-based pathogen [1]. 1959, the United Kingdom, the United States also occurred in California, pop. 1972 enterovirus 71 (EV71) was first recognized in the United States. Since then infected with EV71 infection and Cox A16 alternately as hand, foot and mouth disease in the major pathogens. 1972 ~ 1973, 1986 and 1999, Australia [2] have occurred in EV71 epidemic, most patients with severe symptoms associated with central nervous system (CNS), some patients have severe respiratory symptoms. The mid-20th century, 70, Bulgaria, Hungary, with the successive outbreaks of CNS as the main clinical features of EV71 epidemic, only Bulgaria has more than 750 cases the disease, 149 were caused by paralysis, 44 people were killed. Britain broke out in the fourth quarter of 1994, along with Cox A16 throughout England Wales caused by the hand, foot and mouth disease epidemic, sentinel surveillance sites were observed in 952