Heart-warming capsule on mice Sedation Efficacy Study.docVIP

 PAGE \* MERGEFORMAT 3 Heart-warming capsule on mice Sedation Efficacy Study [Abstract] Objective: To observe the sedative effect of warm heart capsules efficacy. Methods: The heart-warming capsule of normal mice or mice of amphetamine self-exciting effects of activities to evaluate the sedative effect of warm capsule, through the observation of heart-warming capsule nikethamide and Dimefline convulsions induced convulsions in mice The incubation period and mortality of heart-warming to evaluate the anticonvulsant effect of capsules. Results: The heart-warming capsules 20,10 and 5mg/kg can be significantly reduced in normal mice and mice of amphetamine self-exciting activities, and significantly prolong nikethamide and Dimefline-induced seizures of the incubation period, significantly inhibited Nicole Brake m-induced convulsion in mice mortality. Conclusion: The heart-warming capsule has obvious sedation. [Keywords:] heart-warming capsule; sedation; pharmacodynamics Heart-warming heart-warming capsule Qi, Michiharu OK stasis effect, for the heart due to gas shortage and other reasons palpitations, convulsions and other symptoms. This study reflects the calm of her main role Pharmacodynamics of research, we now report the results as follows. 1 Materials 1.1 Drugs and reagents Warm capsule prepared by the Guangdong Provincial Hospital of Chinese hospital preparations, from the tuber, red ginseng, Chinese medicine composed of 37, etc.; Yin sedative pills, Changchun, People’s Pharmaceutical Co., Ltd. production; Dimefline injection, Shanghai No. 1 Biochemical Pharmaceuticals Limited production; amphetamine injection, Huaihai Pharmaceutical Co., Ltd. production. 1.2 Animals NIH mice, cleaning grade, of either sex by the Experimental Animal Center of Sun Yat-sen. 1.3 Instrument XZ-4 type mice independent activity meter, Institute of Materia Medica, Chinese Academy of production. 1.4 Statistical Methods All measurement data is expressed as x ± s, t-test;