Hepatocellular carcinoma hepatocyte growth factor mRNA expression and clinical significance of quantitative.docVIP

 PAGE \* MERGEFORMAT 14 Hepatocellular carcinoma hepatocyte growth factor mRNA expression and clinical significance of quantitative Of: Pu Jian, Wang Jian early Weizhong Heng, Li Liangbo, Wei Jian-bao, Yanhao Ran, Qin Zhijian [Abstract] Objective of the primary tumor tissue, cancer tissue and normal liver hepatocyte growth factor (HGF) mRNA were measured quantitatively analyze the expression and clinical characteristics, and to explore its clinical significance. Methods Using real time quantitative PCR detected 59 cases of primary hepatocellular carcinoma, the corresponding adjacent tissues and 17 normal liver tissue HGF mRNA expression, analyzed the expression of gender, age, serum HBsAg, AFP, differentiation, tumor size, clinical period, transfer status, and whether the clinical features of liver cirrhosis. Results HGF mRNA in primary HCC, adjacent tissues and normal liver showed no significant (Pgt; 0.05.HGF mRNA in hepatocellular carcinoma cirrhotic group was significantly higher than in the cirrhosis group (P lt;0.05, but it has nothing to do with the other clinical features. Conclusion HGF mRNA in the liver cirrhosis tissues showed high expression, suggesting that may be related to the development of liver cancer. [Keywords] Polymerase chain reaction liver tumor hepatocyte growth factor oncogene protein c-met A clinical study on human HGF messenger RNA expression and its clinical implications in primary hepatocellular carcinoma PU Jian, WANG Jian-chu, WEI Zhong-heng, LI Liang-bo, WEI Jian-bao, YAN hao-ran, QIN Zhi-jian Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China Abstract: Objective To investigate the expression of hepatocyte growth factor (HGF) mRNA and analyze whether HGF mRNA expression levels correlate with clinicopathologic variables in patients with primary hepatocellular carcinoma (HCC). Methods Tissue samples, including 59 cancerous, adjacent non-cancerous tissues and 17 no