HJD pharmacological treatment of Alzheimers Research.docVIP

 PAGE \* MERGEFORMAT 17 HJD pharmacological treatment of Alzheimer’s Research Study: Song Jianfang, while Lam, Wang Hongjie [Keywords:] HJD; pharmacology; senile dementia; Summary HJD from lt;lt;elbow backgt;gt;, on behalf of Department of detoxification prescription, from Coptis, Phellodendron, baicalin, gardenia composition, attending a Miami drug effective, triple burner and Heat of the card [1]. Modern pharmacological studies have shown that berberine Decoction of the tumor, cerebral ischemia, diabetes and other diseases with good effect, especially in senile dementia (AD) reported more respect. the author on the basis of extensive literature references, sorted and summarized in AD, HJD Pharmacological Research, to provide reference for related research. An anti-inflammatory Autoimmune disease and age were positively correlated, the body’s immune defense, immune surveillance, immune dysfunction and stability of three, will lead to increase in autoimmune diseases. AD patients significantly reduced the level of thymic hormone, interleukin -1 (IL- 1) overexpression led to proliferation of glial cells, inducing the premise of β-amyloid protein gene (β-APP) expression was increased, tumor necrosis factor (TNF-@) in AD patients with elevated levels of serum, and TNF-@ the nerve toxic to cells [2]. HJD that has been used for the treatment of acute infectious diseases and infectious diseases, pharmacological studies show that it has good anti-bacterial, anti-inflammatory, enhancing immune function. Qin et al [3 ] studies have shown that HJD can significantly reduce capillary permeability and xylene-induced mouse ear edema was significantly affected, while in mice induced by acetic acid writhing and hot stimulation threshold effects are significant , demonstrated its anti-inflammatory analgesic effect; another, but also significant against the intraperitoneal injection (ip) increased capillary permeability induced by acetic acid, indicating that anti-