HPLC determination of allergy rhinitis Ephedrine Capsules.docVIP

 PAGE \* MERGEFORMAT 9 HPLC determination of allergy rhinitis Ephedrine Capsules Of: Zhong Xiaoming Zhang Jing Huang Zhen Jiao Panai Juan Feng Chunrong [Abstract] spirit in the establishment of allergy rhinitis HPLC method for determination of ephedrine. [Methods] Chromatography conditions: column: DiamonsilTM (Diamond C18 (250mm 4.6mm, 5m, mobile phase of acetonitrile-0.02mol / L phosphate monobasic - - K + solution (containing 0.2% triethylamine, adjusted with phosphoric acid PH value to 2.7 = (5:95, flow rate 1.0ml/min, detection wavelength 210nm, column temperature 30 . [Results] The linear range of ephedrine hydrochloride 0.2148 ~ 2.148g/ml, r = 0.9999, average recovery was 98.85%, RSD = 2.95%. [Conclusion] The method is simple, accurate, reproducible, and can be used in the determination of ephedrine allergy rhinitis method of Ling . [Keywords:] allergy rhinitis capsule, ephedrine hydrochloride, HPLC Abstract: [Objective] To establish a method for determination of Ephedrine Hydrochloride in KMBYL capsules by HPLC. [Methods] The DiamonsilTM C18 (250mm 4.6mm, 5 mcolumn was used. The mobile phase was mobile phase: acetonitrine-0.02 mol L -1potassium dihydrogen phosphate (0.2% triethylamine, adjusteding pH to 2.7 with phosphoric acid (5:95 with a flow rate of 1.0ml min-1. The detection wavelength was 210 nm. The column temperature was 30 . [Results] The linear responses range was 0.2148 2.148 g? mL-1 of Ephedrine Hydrochloride (r = 0.9999. The average recovery was 98.85% and the RSD was 2.95%. [Conclusion] The method is simple accurate reproducible.It can be used for the quality control of KMBYL Capsules. Keywords:: KMBYL Capsules; Ephedrine; ‘HPLC’ Allergic rhinitis is a common disease account for about 10% of the population, epidemiological survey of allergic rhinitis and atopic cough incidence rates have gradually increased [1], has become a public health problem of global concern [ 2]. Western control of allergic rhinitis although si