IL9 patients with allergic rhinitis in peripheral blood mononuclear cells the expression level.docVIP

 PAGE \* MERGEFORMAT 14 IL9 patients with allergic rhinitis in peripheral blood mononuclear cells the expression level Of: Wei Zou Ji-hsiang, Chen Qian Chen Jianguo Lin Zhiqiang Yang Meets the Prophet Wang Shengjun [Abstract] Objective: To detect IL 9 patients with allergic rhinitis, the expression level of IL 9 in the development of allergic rhinitis. Methods: 49 patients collected blood samples of patients with allergic rhinitis, in which no treatment 30 cases, 19 cases of clinical remission, another 30 healthy volunteers to take blood samples as normal controls. using real time quantitative PCR (QRT PCR) detected IL 9 gene expression in the peripheral blood, enzyme-linked immunosorbent assay test (ELISA) detected levels of plasma IL 9. Results: Allergic rhinitis is not treated peripheral blood mononuclear cells IL 9 mRNA expression and plasma IL 9 was significantly higher than clinical remission of allergic rhinitis group and the normal control group ( P lt;0.05), and clinical remission of allergic rhinitis compared with normal control group the difference was not statistically significant. Allergic rhinitis is not treated IL 9 mRNA expression levels correlated with clinical scores. Conclusion: Patients with allergic rhinitis, peripheral blood mononuclear cells showed high expression of IL 9. IL 9 may be involved in the pathological process of allergic rhinitis, the specific mechanism needs further study. [Keywords:] allergic rhinitis; interleukin-9; real time quantitative PCR Expression of IL 9 in peripheral blood mononuclear cellwith allergic rhinitis patients JI Jun xiang1, QIAN Wei1, ZOU Chen1, MA Yong ming1, LIN Zhi qiang1, CHEN Jian guo1, YANG Xian zhi2, WANG Sheng jun2 (1.Department of Otolaryngology, the Affiliated People’s Hospital of Jiangsu University, Zhenjiang Jiangsu 212002; 2.Department of Immunology, School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang Jiangsu 212013, China) [Abstract] Objec