Injection pain must be clear in the CCI rat peripheral blood levels of NO.docVIP

 PAGE \* MERGEFORMAT 8 Injection pain must be clear in the CCI rat peripheral blood levels of NO [Abstract] Objective: To investigate the pain must be injection on the CCI (chronic sciatic nerve ligation injury) in rats with peripheral serum levels of NO. Methods: nitrate reductase method, were measured before and after administration of rat peripheral serum levels of NO, by contrast, research on pain, injection must be clear in the CCI rat peripheral blood levels of NO. Results: The pain injection will significantly reduce the CCI in rats with peripheral serum levels of NO. Conclusion: The pain must be clear by inhibiting the CCI rat peripheral blood or release of NO generation to achieve analgesic effect. [Keywords:] pain must be injection; analgesic; NO Injection pain must be from the four kinds of traditional Chinese medicine (active ingredient or parts) consisting of a proprietary Chinese medicine has a good analgesic effect. Of nitric oxide (NO) is a free radical nature of gas, is a new type of messenger molecule in peripheral nerve, the nerve center of the spinal cord level and the level of the spinal cord on three different levels of participation in pain modulation, research must be injection pain peripheral serum NO levels in animals, the effects of the analgesic effect of play, the author made the following studies, the report is as follows. 1 Materials and methods 1.1 Material animals: two healthy Wister rats were 60 pure-bred animals qualified证号 : SCXK  (Kyrgyzstan) 2003  0001. 6-week-old, male, female evenly divided ,180-220g, from the Experimental Animal Center of Jilin University , animal rearing environment, quiet, good ventilation and air filtration system, at room temperature maintained at 20 ℃ , humidity 40%, daily replacement of cages, litter. Main instruments and reagents: sodium pentobarbital, import packaging and Shanghai love purple Special Biological Technology Co., Ltd.; 4  0 Number of medical chrome catgut, Zhengzhou off