Levofloxacin triple therapy for Helicobacter pylori eradication efficacy of salvage therapy.docVIP

 PAGE \* MERGEFORMAT 8 Levofloxacin triple therapy for Helicobacter pylori eradication efficacy of salvage therapy [Abstract] Objective To observe the levofloxacin-based, remedial treatment of H. pylori eradication efficacy and adverse reactions. Method to conventional triple therapy failed to eradicate H. pylori in patients 87 cases were randomly divided into two groups, the observation group, 44 cases given to levofloxacin-based triple rescue therapy. the control group of 43 patients received conventional quadruple rescue therapy, were followed up one month to observe the efficacy and adverse effects in both groups. Results There was a considerable rate of H. pylori eradication (Pgt; 0.05, The incidence of adverse events was no significant difference (Pgt; 0.05. Conclusion levofloxacin-based Helicobacter pylori eradication therapy, medication is relatively simple, patient compliance is good, is a choice of new programs. [Keywords:] levofloxacin, Helicobacter pylori, rescue therapy Helicobacter pylori chronic gastritis and peptic ulcer is an important virulence factor, is also related to gastric cancer and gastric malignant lymphoma of the important pathogenic factor [1]. Their infection, eradication programs currently used for the proton pump inhibitor plus two antibiotics in triple therapy. According to the 2000 European Study Group recommended HP [2] first-line therapy, the use of proton pump inhibitor + clarithromycin and amoxicillin, when treatment failure, the claim given with bismuth quadruple therapy as rescue therapy. However, with the increase in antibiotic resistance, and poor compliance with a number of reasons, there are still some patients with H. pylori infection has not been an effective cure, so look for more effective eradication of H. pylori or a remedy is necessary. the author of levofloxacin-based triple therapy for Helicobacter pylori cure remedy the failure of treatment, and with the European Study Group recommended HP quadruple