Local injection of tetanus antitoxin 1 case of delayed reaction.docVIP

 PAGE \* MERGEFORMAT 3 Local injection of tetanus antitoxin 1 case of delayed reaction [Abstract] 1 case of tetanus antitoxin delayed skin test reaction of the local patient care, that care should be observed to enhance the effect after administration, timely and accurate processing of adverse drug reactions and make health education. [Keywords:] tetanus antitoxin, skin test, drug reactions, nursing 1 Clinical data Patients, female, 40 years old, because of the hand skin abrasions (about 1cm 3cm 36 hours after treatment, prescribed by a doctor to give tetanus antitoxin (TAT skin test result is negative, intramuscular TAT1500, observed 30min, no local swelling, induration, pseudo-foot, blisters, itching and other adverse reactions .5 d later, the patient left forearm skin test site appears red papules, a diameter of about 3cm, right buttock intramuscular injection site appears 2cm 3cm irregular pink rash, with itching and discomfort, condensate as urticaria, oral chlorpheniramine 1.5mg, Vitamin C 0.2g. The next morning, right subcutaneous intramuscular injection site swelling, stiff, itching. noon intramuscular injection site hard swelling, fever, gradually expanded to 10 cm 15cm, itching , but the left forearm to alleviate the symptoms of red papules, once again diagnosed as drug allergy treatment induced local delayed reaction. 30% of magnesium sulfate given to the local doctor moist heat, 3 times a day, intravenous injection of 5% glucose 10mL +10% calcium gluconate 10mL + dexamethasone 5mg, treatment of 3d, red pimples skin test site dissipated, intramuscular injection to reduce swelling of the hard parts , moist heat to the hip line, 7d after the symptoms completely subsided. 2 Discussion In this case, after injection of tetanus antitoxin 5d allergic reactions to local skin symptoms, less common. Recount a history of allergies, the patient was 10 years ago, the private prosecutor injected TAT, no response. Trace the fam