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Metabonomics technologies and their integration in the Western Research Prospects
PAGE \* MERGEFORMAT 23
Metabonomics technologies and their integration in the Western Research Prospects
Author: Wu Bin, Yan Shi-Kai, Shen Yin, Zhang Weidong
[Keywords:] Metabolomics; Zhong Xi Yi Jie; Medicine; Review
Metabolomics is the second of genomics and proteomics developed after a research group that studies biological systems approach. It is the United Kingdom, Professor Nicholson and his colleagues formally proposed in 1999 [1]. Metabolomics refers to ‘a cell, tissue or organ, all the set of metabolic components, in particular, refers to small molecules’, which metabolomics is a’ dynamic process in the metabolism, the systematic study of the changes in metabolites the law of life activity metabolism of the body reveals the essence of ‘science [2], It is concerned with the relative molecular mass of less than 1 000 small molecules. In recent years, metabolomics research has attracted the attention of many researchers, metabolomics and genomics and proteomics is different genomics and proteomics tell you what might happen, and metabolomics will tell you what has taken place; also Researchers believe that metabolomics is a ‘group learning’ study of the terminal [3]. In order to better group of technologies used in the metabolism of Medicine study, the paper in recent years in foreign-related information on the metabolomics experimental techniques, analytical techniques and their application status in modern medicine were reviewed, while Metabolomics in Integrative Medicine in the development trend is prospected.
1 metabolomics experimental technique
1.1 Metabolism Research Group common technique for metabolomics studies used nuclear magnetic resonance (nuclear magnetic resonance, NMR) and mass spectrometry techniques, such as gas chromatography mass spectrometer (gas chromatography mass spectrometer, GC MS) and liquid phase chromatography mass spectrometer (liquid chromatography mass spectrometer, LC MS), etc. [4]. NMR spectrosc
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