Methods of drying the extract of Smilax diosgenin content of.doc

 PAGE \* MERGEFORMAT 10 Methods of drying the extract of Smilax diosgenin content of [Abstract] Objective To compare the different drying methods on Smilax extract diosgenin content in the impact. Methods RP  HPLC method (column of ODS  C18 (4.6 mm * 250 mm, 5 μ m) stainless steel column, mobile phase was methanol, detection wavelength was 203 nm, peak area quantified by external standard) determination of Smilax extract of diosgenin content, examining spray drying method, drying at atmospheric pressure and vacuum drying effects. The results of the extract spray drying method in the destruction of diosgenin content in the least measured obtaining the content of 0.0869 mg / g, ambient pressure drying method and decompression drying levels measured were 0.0721,0.0588 mg / g. Conclusion Smilax extract the best drying method is spray drying method. [Keywords:] Smilax extract spray drying method of vacuum drying drying drying at atmospheric pressure Smilax Smilax extract capsules are made of proprietary Chinese medicine clinic for the treatment of chronic pelvic inflammatory disease, Annex inflammation, accessories inflammatory mass, the exact effect. In the King Kong vine during the preparation of capsules, dry capsules are prepared Jingangteng an important part of the process. Drying using scientific methods, not only can save energy, reduce drying time and reducing the loss of active ingredients, improve product quality. Diosgenin is a major active ingredient Jingangteng [1]. To this end, this paper study of diosgenin content in atmospheric pressure drying method, vacuum drying and spray drying of the extract of Smilax diosgenin impact. An apparatus and materials Spray Dryer (EYELA  SD  1000 type), vacuum drying oven (ZK  82B-type), Waters 2695 high-performance liquid chromatograph, 2996 UV detector, microporous membrane (0.45 μ m); diosgenin reference substance (China Pharmaceutical and Biological Products Institution, Lot 1539  200001), Dia