Methotrexate treatment of ectopic pregnancy mifepristone clinical analysis of 63 cases.doc

 PAGE \* MERGEFORMAT 6 Methotrexate treatment of ectopic pregnancy mifepristone clinical analysis of 63 cases [Keywords:] ectopic pregnancy Ectopic pregnancy refers to the fertilized egg implantation in the uterus outside the body cavity, often called an ectopic pregnancy is one of common gynecological acute abdomen. With the highly sensitive radioimmunoassay -human chorionic gonadotropin (HCG), B ultrasound and laparoscopy advances in diagnostic techniques, early diagnosis of tubal pregnancy rate was significantly improved, so the majority of patients conservative treatment is increasingly accepted [1]. our hospital with methotrexate and mifepristone treatment of unruptured ectopic pregnancy in 70 cases, achieved good results, the final report is as follows. 1 Subjects and methods 1.1 study Our hospital from October 2004 to September 2007 patients were treated 178 cases of ectopic pregnancy. The median age was 27 years old (19 to 45 years old, met the inclusion criteria for conservative treatment of ectopic pregnancy in 63 patients. Randomly divided into control group and observation group. the control group 33 cases, the use of single injection of methotrexate; observation of 30 patients, the use of methotrexate injection compatibility mifepristone. 1.2 Inclusion criteria Vital signs were stable, without active bleeding, ultrasonography, ectopic pregnancy outside the uterine cavity prompted mass diameter lt;5 cm, no pelvic fluid or lt;2 cm, -HCG lt;3 000 mU / mL, the young growth or demand required conservative treatment; blood and liver, renal function was normal; without methotrexate and mifepristone medical contraindications [2]. 1.3 Methods Randomly divided into 2 groups: observation of 30 patients given a single intramuscular injection of methotrexate 50 mg/m2; while mifepristone, each 50 mg, 3 times / day, 3 days for a course of treatment. Every 3 days -HCG blood test and ultrasound 1, vaginal bleeding and abdominal pain were