Metoprolol in patients with rheumatic heart disease patients with paroxysmal AF of Pd.docVIP

 PAGE \* MERGEFORMAT 9 Metoprolol in patients with rheumatic heart disease patients with paroxysmal AF of Pd Keywords: wave dispersion P wave dispersion (Pd) is a prediction of paroxysmal atrial fibrillation (AF) an effective indicator of the surface ECG. Paroxysmal atrial fibrillation is a common complication of rheumatic heart disease. Metoprolol can effectively control ventricular rate, reverse or delay the cardiac remodeling. This study assessed the impact of its Pd. 1 Data and methods 1.1 General Information Select from May 2006 to August 2007, in the hospital outpatient echocardiography in mitral stenosis prompted cardiac function in the two above, do not need anti-heart failure therapy rheumatic heart disease, patients with paroxysmal AF 74 cases, male 26 cases, female 48 cases; aged 44 to 78 years, the average (60.8 ± 11.0) years of age. All the patients began taking metoprolol without two weeks before the application of anti-arrhythmic drugs, cardiac drugs, diuretics. Given small doses of oral metoprolol 6.25mg, 2 times / d. Per week increase in the dose to the target volume of 50mg, 2 times / d, heart rate “55 times / min, used in conjunction for 6 months. Before and after the experiment to give the liver, kidney function, electrolytes, blood routine examination two times, resulting in no statistically significant difference, not to the contents of this experiment. Paroxysmal atrial fibrillation occurs, the role of early-onset amiodarone control room. Which five cases of heart rate “55 times / min, to be phased reduction, improved 2 weeks after drug withdrawal. No case of this experiment. Measure 1.2 Were recorded before and after oral administration of metoprolol simultaneous 12-lead conventional electrocardiogram (ECG), take the paper speed 50 mm / s, gain 20 mm / mV, each lead record of not less than five sinus P wave. Manual visual method using the same person lead P-wave measurement of the time value