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Mifepristone with misoprostol on termination of 10 to 16 weeks of pregnancy
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Mifepristone with misoprostol on termination of 10 to 16 weeks of pregnancy
[Keywords:] mifepristone misoprostol for termination of pregnancy 10 to 16 weeks
For the past 10 to 16 weeks of pregnancy to terminate the pregnancy, pregnant women, the use of intra-amniotic injection of lactic acid or amniotic Ethacridine outside the injection of lactic acid Ethacridine line clamp curettage abortion method, this method requires the uterine cavity operation, an increase of uterine injury and intrauterine infection in pregnant women the chance. In recent years, the Court adopted Mifepristone (the “misoprostol”), 10 to 16 weeks of pregnancy termination method of reducing surgical complications, higher success rate, reported as follows.
Subjects and Methods
1. Target: 5 December 2007, 200 cases of pregnant 10 to 16 weeks to terminate pregnancy in healthy women without reproductive tract abnormalities, acute and chronic disease, especially no cardiovascular, blood and endocrine system diseases, no history of multiple drug allergy and no history of recurrent vaginal bleeding, the gynecological examination and B-ultrasound confirmed a normal intrauterine pregnancy, urine routine, the clotting time, platelets, liver function and ECG were normal. selected object sublingual hospital were randomly divided into groups and vaginal misoprostol treatment group, 100 cases in each.
2. Medication methods: Mifepristone, each 25mg, misoprostol, each 200 μg, Beijing Zizhu Pharmaceutical Co., Ltd. production. 2 h before breakfast, mifepristone 50 mg, 2 h after dinner mifepristone 25 mg, warm water, 3 Tianzao 8 admission. Sublingual group of 400 μg of sublingual misoprostol , 2 h after the weak and irregular contractions or contractions continue sublingual misoprostol 200 μg. vaginal misoprostol vaginally treatment group 400 μg, supine, 2 h after the contractions or contractions irregular vaginal administration of misoprostol is still weak 200 μg, birt
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