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Minimal change nephrotic syndrome hormonal and Chinese medical treatment
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Minimal change nephrotic syndrome hormonal and Chinese medical treatment
Minimal change nephrotic syndrome (MCNS) is a common pathological type, accounting for 10 years of age children with primary nephrotic syndrome in 80% ~ 90%, adult primary nephrotic syndrome in 20% to 30%, can be divided into primary and secondary clinical practice mostly primary, in which mainly discussed by the primary minimal change nephrotic syndrome caused by this type. The pathological features a group of normal glomeruli by light microscopy, electron microscopy of glomerular epithelial cell foot process fusion and diffuse foot process hole is characterized by occlusion of primary glomerular disease. Sensitive to hormone therapy, prognosis is good. However, the hormone does not alter the natural course of the disease, not prevent recurrence. In recent years, Chinese medicine combined hormone therapy with minimal change nephrotic made some progress, reducing recurrence, this article will conduct a review.
1 MCNS a natural progression and prognosis of
Minimal-change mitigation and natural hair as a feature of repeated, long-term follow-up of children and adults hormone effective minimal change nephrotic syndrome results, in general, the prognosis is good, Cameron reported survival rate of the Decade amp;quot;95%, most of those who died as adults, and developed into a rare chronic renal failure, adult development to 3% of chronic renal failure, children are more rare. Chronic renal failure often occurs in those who are resistant to the hormone, while each additional with focal glomerular sclerosis [1].
2 MCNS Treatment of the purpose of
2.1 Control of a large number of long-term proteinuria proteinuria can cause severe complications such as infection, thromboembolism, acute renal failure; also lead to renal fibrosis, develop into chronic renal failure. In the therapy, to improve the glomerular filtration membrane barrier function, reduce urinary protein, pre
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