Mifepristone and misoprostol combined with phloroglucinol for efficacy of mid-pregnancy induction.docVIP

 PAGE \* MERGEFORMAT 5 Mifepristone and misoprostol combined with phloroglucinol for efficacy of mid-pregnancy induction [Keywords:] trimester abortion, mifepristone, misoprostol, phloroglucinol Our hospital in 2004 and 2007 32 cases of 18 to 27 weeks of pregnancy to terminate the pregnancy voluntarily given mifepristone and misoprostol combined with phloroglucinol termination of pregnancy, the effect is good, are as follows. 1 Materials and Methods 1.1 General data selection to terminate the pregnancy in our hospital from 18 to 27 weeks pregnant women in 32 cases, aged 17 to 42 years (of which 12 cases of primipara, the maternal 20 cases of uterine scar in 1 case, willing to accept mifepristone m misoprostol to terminate the joint phloroglucinol pregnancy, admission B-ultrasound routinely recognized as intrauterine pregnancy, the placenta normal position, excluding non-gynecological examinations and acute infections of reproductive tract abnormalities, blood, the clotting time, liver and kidney function examination were normal, no contraindications of these drugs are. 1.2 drugs mifepristone (25 mg / tablets, misoprostol (0.2 mg / tablets, were Beijing Zizhu Pharmaceutical Co., Ltd. production. Phloroglucinol powder (40 mg / support, Hubei Pharmaceutical Company Limited noon company. 1.3 Methods of mifepristone 75 mg, day 1, and even served 2 days, 3 days into the morning vaginal misoprostol, the initial amount of 0.1 ~ 0.4 mg, after 6 h of treatment the symptoms not obvious, as appropriate contractions a small amount (usually 50 μg misoprostol was added, the total does not exceed the daily 1.2 mg. until labor occurs when the intravenous injection of phloroglucinol 40 ~ 80 mg. 2 Results 2.1 The effect of induction of labor contractions after the first use of misoprostol for the longest time not more than 3 h, regular contractions to the fetal placenta minimum 3 h, a maximum of 12 h.32 successful induction rate of 100% cases, the placenta