Mixed-effects linear model univariate analysis of variance with repeated measurement data in the application of comparative.doc

 PAGE \* MERGEFORMAT 14 Mixed-effects linear model univariate analysis of variance with repeated measurement data in the application of comparative Keywords: repeated measurements; mixed effects linear model; single-factor analysis of variance; Abstract: Objective: The mixed effects linear model univariate analysis of variance with repeated measurement data in the application of comparison, intended to illustrate two ways in dealing with repeated measurements data of the application characteristics. Methods: Using mixed effects linear model and a single-factor analysis of variance repeated measurement data processing and to compare. Results: The mixed-effects linear model and a single-factor analysis of variance repeated measurement data are an important deal with statistical methods, the former in the choice of covariance structure may be on repeated measurements of the fixed effects and random effect parameters and covariance matrix Parameter estimation and statistical tests, which are available on repeated measurement data to make statistical inference for fixed effects. Conclusion: The mixed-effects linear model to deal with a powerful method of repeated measurement data, it requests information on the covariance structure of relaxed, and the conclusions and reliable; single-factor analysis of variance covariance structure of the data, there are strict qualification. Keywords:: repeated measurements; mixed effects linear model; single-factor analysis of variance; Of statistical methods characterized by repeated measurements (repeated measures data) is the medical field in the common form of data. The so-called repeated measurement is an observation of the same object at different time points on multiple measurements [1]. As the repeated measurement data is a particular object of the same subjects repeated observation of indicators observed data, the same subjects observational data correlation may exist between a number of tradition