Moderate-intensity treadmill exercise on bone mass in ovariectomized rats and serum sex hormone levels associated.doc

 PAGE \* MERGEFORMAT 14 Moderate-intensity treadmill exercise on bone mass in ovariectomized rats and serum sex hormone levels associated Of: Bo Shumin Mr Chan Wang Yingjie Hao Transfer Abstract Objective To observe the moderate-intensity treadmill exercise on bone mass in ovariectomized rats and serum sex hormone levels related to the impact of the prevention of postmenopausal osteoporosis in rats. Methods 40 female SD rats without the production, were randomly divided into sham, ovariectomized rest, exercise and estrogen in ovariectomized 4. Ovariectomized 4 times a week exercise group 45 min, speed of 18 m / min, 5 slope treadmill training; estrogen group 3 times per week subcutaneous injection of estradiol 17 , each 50 g / kg body weight . After weighing the weight of intra-abdominal fat and uterus; serum estradiol (E2), progesterone (P4) and testosterone (T) content; detection of the right femur and tibia free bone mineral density (BMD) and bone mineral (BMC ) content. Results moderate-intensity treadmill exercise can significantly increase the proximal femur in ovariectomized rats, the middle and distal and proximal tibia BMC, BMD and serum E2 levels were significantly lower in ovariectomized rats intra-abdominal fat mass and serum P4 and T levels. Conclusion moderate-intensity treadmill running against bone mass in ovariectomized rats at least in part the decline may be related to the regulation of serum sex hormone levels. Keywords: exercise; ovariectomized rats; bone mineral density; hormone Abstract Objective To observe the effects of moderate intensity treadmill exercise on bone mass and related serum sex hormones in ovariectomized rats. Methods Forty 3 month old female SD rats were either sham operated (SHAM) or ovariectomized (OVX) and randomly divided into four groups by body weight: SHAM, OVX, OVX rats treated with exercise (EX group, 18 m / min, 5% uphill, 45 min / day, 4 times / week), OVX rats treated with 17 estrogen gr