Molecular aggregation and surface adsorption of magnetic nanoparticles of ac susceptibility.doc

 PAGE \* MERGEFORMAT 22 Molecular aggregation and surface adsorption of magnetic nanoparticles of ac susceptibility Of: Zhuangke Hu, Wang Chunyu, Zhang Yu, Ning Gu [Abstract] Objective: To study the molecular aggregation and surface adsorption of magnetic nanoparticles of AC susceptibility for the development of magnetic nanoparticles based on magnetic susceptibility measurements provide the basis for bio-sensing method. Methods: Transmission electron microscopy and vibrating sample magnetometer of magnetic nanoparticles were magnetic core particle size, magnetic properties were measured, using laboratory measurements of ac susceptibility self-built device, the different aggregation states in the adsorption and surface antigen, antibodies and other biological molecules of ac susceptibility of magnetic nanoparticles spectra were measured. Results: Transmission electron microscopy measurements show that the iron oxide nanoparticles used in this experiment the average diameter of magnetic core 10 nm, but due to the solution of the magnetic dipole interactions between particles and to form aggregates, showed a greater hydrodynamic size and its distribution. vibrating sample magnetometer measurements show that the iron oxide nanoparticles, the saturation magnetization for the 61.43 emu g-1. ac susceptibility measurements show that the spectrum, with the iron oxide particles in the solution hydrodynamic size increases, the aggregate size increases, the magnetic susceptibility spectrum of dynamic characteristics of the corresponding frequency decreases, consistent with the theory indicates. When the buffer solution, adsorption of magnetic nanoparticles and the further integration of IgG and goat anti-human IgG, the magnetic dynamic characteristic frequency decreases, which is caused by surface adsorption gradually increased hydrodynamic size of the result is the same. Conclusion: The solution of the aggregation state of magnetic nanoparticles and bio-molecular