Mount four-leaf polysaccharide on young mice and the immune regulation of the immune mice.doc

 PAGE \* MERGEFORMAT 15 Mount four-leaf polysaccharide on young mice and the immune regulation of the immune mice Of: Wang before, Qiuyu Yu, Zhang Xianzhong, Gao Lijun [Abstract] Objective To observe leaf polysaccharide from Mount (PCL immune suppression in young mice and immune mice. Methods The mice were randomly divided into saline control group, cyclophosphamide (CTX control group, PCL group (200 mg kg-1 d-1 and CTX and PCL with high, medium and low doses (100,200, 400 mg kg-1 d-1 combination group, continuous ig 14 d, thymus and spleen, macrophages phagocytosis and serum specific anti-sheep red blood cell (SRBC antibody IgM, IgG levels and detection of 0.5 ~ 16.0 mg ml-1 PCL 6 geometric design concentration on in vitro proliferation of mouse spleen lymphocytes. Results PCL young mice significantly increased the thymus index and spleen index, macrophages, red blood cells of chicken (CRBC phagocytic rate and phagocytic index, increased serum anti-SRBC antibody levels, and promote lymphocyte proliferation in vitro in a dose dependent manner antagonized CTX immunosuppression in mice. Conclusion PCL immune suppression in young mice and mice of non-specific and specific immune functions were significantly enhanced role. [Keywords:] Tarzan four leaf parameters, polysaccharides, cyclophosphamide, immune regulation Abstract: ObjectiveTo investigate the immunoregulation of polysaccharides extracted from Radix Codonopsis Lanceolatae from Mount Taishan (PCL) in juvenile and immunosuppressed mice. MethodsThe juvenile mice were divided randomly into six groups, namely, normal saline control, cyclophosphamide (CTX) control, PCL (200mg kg-1 d-1group, and three combination groups (CTX and 100,200, 400mg kg-1 d-1 PCL). After given orally for two weeks, the thymus and spleen index, the celiac macrophage ability of engulfing CRBC , and the antibody level of serum against SRBC were determined. Effects of six concentration levels of PCL on spleen lymphocyte