Multiple indicators combined detection of autoantibodies and the relationship between HBV DNA analysis.doc

 PAGE \* MERGEFORMAT 7 Multiple indicators combined detection of autoantibodies and the relationship between HBV DNA analysis Of: Guo Ping Huang Jie Luo Jia Florence [Abstract] Objective: To investigate the autoantibodies and hepatitis B virus infection. Methods: Determination of enzyme immunoassay dot anticardiolipin antibodies in patients with hepatitis B (ACA), anti-smooth muscle antibodies (ASMA), anti-nuclear antibody (ANA) . Results: 45 cases of hepatitis B patients with ACA, ASMA, ANA positive rate was significantly higher than the control group (P lt;0.05). autoantibodies in experimental group and the HBV DNA real-time fluorescent quantitative PCR results to the corresponding relationship between the ACA 8 cases, the positive rate was 17.78%; AMSA 7 cases, the positive rate was 15.56%; ANA 10 cases, the positive rate was 22.23%; and the spectrum of liver enzymes ALT, AST, GGT relationship between the performance of ACA 10 cases, the positive rate 22.23%; AMSA 3 cases, the positive rate was 6.67%; ANA 12 cases, the positive rate was 26.67%; HBV DNA real-time fluorescent quantitative PCR on the value gradient and the release of spectrum is proportional to the liver enzyme. Conclusion: ACA, ASMA and ANA production nothing to do with whether infected with hepatitis B, but hepatitis B virus is active and the degree of liver damage. [Keywords:] hepatitis; HBV DNA; autoantibodies China is a high incidence of hepatitis B [1], a serious threat to people’s health. In hepatitis B patients, due to complexity of pathogenic factors, resulting in different clinical and pathological changes. There are indications of hepatitis B does not directly lead liver cell damage, which is due to exacerbations caused by the body’s immune response [2]; for the production of autoantibodies and real-time fluorescence quantitative PCR HBV DNA on the value of the relationship and significance of the February-May 2009, 45 cases of our hospital Quantitative real-time fluoresc