MS Contin treatment of pain in 82 cases of dose distribution analysis of.doc

 PAGE \* MERGEFORMAT 6 MS Contin treatment of pain in 82 cases of dose distribution analysis of [Keywords:] MS Contin dose distribution characteristics of pain Treatment of patients with cancer pain is increasingly being everyone’s attention, control of cancer pain is an important clinical oncology one of the elements. Currently existing cancer patients around the world about 140 million, of which 30% ~ 60% accompanied by varying degrees of pain, and nearly half are not limited control, directly affecting the quality of life of patients, so this study application of MS Contin Treatment 82 cases of advanced cancer pain, results were satisfactory. Are reported below. 1 Materials and Methods 1.1 General information select from April 2005 to April 2007, Zhejiang Xiaoshan hospital during the initial use of MS Contin treatment of cancer pain in advanced cancer patients are diagnosed as malignant by pathology, continuous regulate the use of MS Contin drug therapy ≥ 4 weeks. 43 cases were males, 39 females, aged 45 to 70 years old, mean age (65.28 ± 4.63) years of age. Visceral pain in cases of 24 cases, 12 cases of physical pain, bone pain and 12 cases, 7 cases of neuropathic pain, mixed pain 27. 1.2 Methods moderate pain group first give MS Contin (Di Meng from Beijing Pharmaceutical Co., Ltd. Production) 10mg, oral once every 12 hours, dose-titration until pain control in the digital Assessment Act (numerical rating scale, NRS) ≤ 3; severe pain group was given MS Contin 20mg orally once every 12 hours, dose-titration until pain control in NRS ≤ 3. Through the NRS to assess their pain intensity, comparative observation of MS Contin for moderate pain (NRS 4 ~ 7,36 cases) and severe pain (NRS 8 ~ 10,46 cases) required daily dosage, different types of daily pain and different doses of MS Contin daily dose of the incidence of adverse reactions. 1.3 statistical methods using SPSS 11.0 statistical software. Measurement data using mean ± standard deviation (■ ),