Mother to child transmission of hepatitis B blockade on the clinical observation.doc

 PAGE \* MERGEFORMAT 5 Mother to child transmission of hepatitis B blockade on the clinical observation [Keywords:] Hepatitis B; mother to child transmission; treatment Hepatitis B virus infection is a worldwide public health problem in recent years, studies have shown that vertical transmission is the main mode of transmission of HBV, which not only caused large population of hepatitis B surface antigen carriers, a serious threat to the quality of our birth, and also contribute to adult chronic hepatitis, liver cirrhosis, and an important factor in liver cancer, according to statistics, perinatal HBV infection by vertical transmission are the future, about 70% of chronic hepatitis B, of which about 25% likely to die of cirrhosis and liver cancer [1]. So blocking HBV perinatal transmission technology is of great significance, our department implemented according to HBV mother to child transmission of antenatal, intrapartum and postnatal prevention of the three stages, and have achieved good results [2]. 1 Clinical data 1.1 Case Selection chosen in January 2007 -2009 during the period of January my mother to child transmission of hepatitis B subjects were blocked by 240 cases of pregnant women, patients were viral hepatitis B patients, including three positive 144 cases, Small three of 96 cases; hepatitis B virus DNA replication of 156 cases positive and negative patients, 84 patients had no pregnancy complications .240. 1.2 Blocking Methods 1.2.1 The use of pregnancy from 28 weeks of pregnancy starting from 4 weeks 200u intramuscular injection of hepatitis B immune globulin to prevent intrauterine infection. 1.2.2 childbirth delivery system of strict implementation of disinfection and isolation to minimize the production process of fetal injury. The best one midwife and the other dealing with newborns; If a person delivery, the baby is delivered after the replacement glove reprocessing newborn; off when the use of umbilical clamp operation,