Molecular markers of joint detection of myocardial infarction on diagnosis of acute myocardial.doc

 PAGE \* MERGEFORMAT 10 Molecular markers of joint detection of myocardial infarction on diagnosis of acute myocardial [Abstract] Objective To explore the acute myocardial infarction (AMI) the most valuable combination of early diagnosis to improve the early diagnosis of AMI. Methods chest pain and suspected acute myocardial infarction AMI group, 98 were divided into 68 cases, 30 cases of non-AMI group , were detected in patients with CK, CK MB, MYO and cTnI. Results AMI in the AMI group MYO 1 to 2 hours after the abnormal peak 5 to 12 hours, significantly earlier than the other three indicators, cTnI and CT MB synchronization However, elevated cTnI in the range of large, long half-life, recovery in 7 to 10 days. Conclusion The early diagnosis of myocardial injury should be based on laboratory indicators of both specificity and sensitivity of the combination of a more optimal combination of cTnI and CK MB should be , conditional hospitals can be CK, CK MB, MYO and cTnI joint detection, more conducive to the diagnosis and treatment of AMI. [Keywords:] Acute myocardial infarction of creatine kinase isoenzyme of creatine kinase myoglobin, troponin I ECG is currently the clinical diagnosis of acute myocardial infarction (AMI one of the most important indicators, however, many AMI patients do not appear characteristic ECG ST segment changes [1]. In recent years, in the world of acute myocardial infarction incidence rate continues to rise, the mortality rate is also high. for the treatment of AMI is the most important time of reperfusion, the time effect and thrombolytic therapy was a negative correlation [2], therefore, early diagnosis and treatment of AMI has of considerable importance. The earliest applications of myocardial necrosis markers are aspartate aminotransferase (AST), followed by a lactate dehydrogenase (LDH), creatine kinase (CK), creatine kinase isoenzyme (CK MB) and so on, CK MB which is considered the diagnosis of AMI gold standard for sero