Musk ginkgo biloba pills rabbit atherosclerotic plaque stability of.doc

 PAGE \* MERGEFORMAT 6 Musk ginkgo biloba pills rabbit atherosclerotic plaque stability of Author: Wang Chih-kang Shen Qin Zheng Hu Li Jian-Ping Shen Cheng Tingting [Abstract] Objective reproduction of experimental rabbit atherosclerosis (AS) plaque model to observe the musk of Ginkgo biloba pills on rabbits AS plaque. Methods 40 rabbits were randomly divided into normal control group, model control group, simvastatin group and musk Ginkgo biloba pills high-and low-dose group, and normal control group was given normal diet, the other experimental group, the supply-induced atherosclerosis feed, feeding 45 d. Observation of musk ginkgo biloba pills on rabbit AS plaque morphology, measured MMP9, fibrous cap thickness, lipid center area, plaque area and aortic aspect of the total number of patches, the number of thrombosis. Results musk Ginkgo biloba pills could significantly reduce the rabbit atherosclerotic plaque fibrous cap thickness and central lipid area ratio, the center area and plaque area ratio of lipid, can reduce the number of patch number and the occurrence of thrombosis, aortic the organization is also the ratio of MMP9 and the protein content decreasing. Conclusion musk Ginkgo biloba pills have a certain stability in rabbit aortic atherosclerotic plaques role. [Keywords:] musk ginkgo biloba pills stability of atherosclerotic plaque Atherosclerotic plaque instability and a variety of participation in atherosclerosis (atherosclerosis, As) form factors. In this paper, experimental rabbit model of AS plaque was observed musk after intragastric administration of Ginkgo biloba pills, AS plaque instability in rabbits on the model explore the effect of ginkgo biloba pills musk plaque stabilizing role of the AS research. Are reported below. 1 Materials 1.1 Animal ordinary class rabbits, male, weighing 2.0 ~ 2.5 kg, were purchased in Jinling Shuto field, qualified证号 : SCXK (Soviet Union) 2002-0025; animal husbandry environment: Experimental Animal Cente