Myocardial energy drink on adriamycin induced myocardial injury.doc

 PAGE \* MERGEFORMAT 8 Myocardial energy drink on adriamycin induced myocardial injury Of: Wang Renping, Zhang Min, Lv Zhixin, Li Qinghua, Xu compliance, Liu Hongxia, Huang Ruixia [Abstract] Objective To investigate myocardial viability drink on adriamycin (ADM) induced myocardial injury and antioxidant effects. Methods ADM induced myocardial injury model. SD 80 rats were randomly divided into 4 groups , n = 20, respectively, the normal control group, model control group, myocardial viability drinking group (10 g raw herbs / kg) and positive drug Astragalus ShengmaiYin group (7 mL / kg). In addition to the normal control group, the other The rats were injected ADM (2.5 mg / kg), 3 times a week for 4 weeks. maturity levels of blood, malondialdehyde (MDA) content and superoxide dismutase (SOD) activity and the cardiac pathology. Results Group and Astragalus myocardial viability ShengmaiYin drink blood and myocardial MDA group was significantly lower than the control group, SOD levels were significantly higher than the model control group, myocardial pathologic score down. Conclusion Myocardial energy drink with anti- oxidation on myocardial injury caused by ADM has a protective effect. [Keywords:] Myocardial energy drink; doxorubicin, malondialdehyde, superoxide dismutase, myocardial injury, rats Abstract: Objective To observe the protective and antioxidative effect of Xinjihuoliyin on the myocardium injury induced by adriamycin (ADM) in rats. Methods 80 SD rats were randomly divided into four groups: normal group, control group, Xinjihuoliyin group and positive control group (Huangqishengmaiyin group). In control group, Xinjihuoliyin group and Huangqishengmaiyin group, ADM was intraperitonial injected at a dose of 2.5 mg / kg, three times every week, for 4 weeks, while normal saline was intraperitonial injected at a dose of 3 mL / kg in normal group. In Xinjihuoliyin group, Xinjihuoliyin was intragastric administrated once a day at a dose of 10 g / k