Myocardial ischemia-reperfusion related genes of.doc

 PAGE \* MERGEFORMAT 13 Myocardial ischemia-reperfusion related genes of [Abstract] myocardial ischemia-reperfusion induced cardiac gene profile changes, and this change is caused by the phenomenon of myocardial ischemic reperfusion injury an important molecular basis of myocardial ischemia-reperfusion induced changes in gene expression studies effective prevention and treatment of myocardial ischemia is of great significance. [Keywords:] myocardial ischemia reperfusion, associated gene Dredge or reconstituted blood vessels after ischemia to reperfusion of ischemic tissue by blood, in most cases the function of ischemic tissue and organ structures restored by reperfusion, but reperfusion has a dual nature, that is sometimes not only can not restore tissue and organ function Instead, the ischemic metabolic disorder caused by functional and structural damage further. Therefore, based on the resumption of blood flow in ischemic tissue is more intense after the damage caused by the phenomenon known as ischemic reperfusion injury (ischemia reperfusion injury) or re- perfusion syndrome (reperfusion syndrome) .1960 Jennings the first time in myocardial reperfusion injury in the concept [1]. Since then, people on ischemia-reperfusion injury in a great deal of research and discussion [2-4]. With the molecular biology the progress of science, it was discovered that myocardial ischemia induced the expression of many genes changed, and this change is caused by the phenomenon of myocardial ischemic reperfusion injury an important molecular basis. myocardial ischemia-reperfusion induced changes in gene expression for the prevention and treatment Myocardial ischemia-reperfusion injury provides a new clue and means, so myocardial ischemia-reperfusion induced the expression of genes related to more and more attention. This study found nearby a few years at home and abroad with myocardial ischemia and reperfusion-related genes as reviewed. 1 apoptosis-related gene (r