Natural plant products on macrophage function in Progress.doc

 PAGE \* MERGEFORMAT 29 Natural plant products on macrophage function in Progress Keywords: natural plant products of macrophages Natural herbal refers to the compatibility of a single or multiple plants that contain specific active ingredients and (or) plant extracts for medical purposes medical products; it derives from natural plant products. Since the 20th century, 90 years in the worldwide rise of the “return to nature” trend and the “Green Movement”, the natural plant medicine were more and more attention and favor. In 2005, sales of natural herbal medicines account for about 30% of total sales, breaking the 26 billion U.S. dollars, and at an annual rate of more than 20% of the rise. Therefore, the development of new drugs from plants is the world’s drug research and development trends and trends. Macrophages are important cells in the immune system, from bone marrow hematopoietic stem cells develop from. The biological function of macrophages wide, in the immune response play an important role in many stages. Mainly include: (1) presenting antigen processing, start-specific immune response; (2) non-specific killing effect of phagocytosis and the secretion of toxic substances activated (H2O2, O-2 and NO, etc.), anti-microbial peptides (defensins, cationic protein, etc.) and enzymes (lysozyme, etc.) to play a killing effect of the product; (3) immune regulation: secretion of cytokines IL-1, IL-6, IL-8, IL-12 and TNF-α, etc.; ( 4) Anti-tumor effect. In immune pharmacology studies, natural plant products on macrophage function is being more and more people’s attention and is expected to develop from a highly efficient immune regulation of new drugs with low toxicity. Now at home and abroad of natural plant products on the macrophage function of research summarized as follows: 1 on macrophage antigen-presenting function of Macrophages with antigen processing, presenting and immune regulation, and role in t