Neonatal acute lung injury Blood Endothelial Growth Factor Expression and significance of changes in.docVIP

 PAGE \* MERGEFORMAT 5 Neonatal acute lung injury Blood Endothelial Growth Factor Expression and significance of changes in Neonatal acute lung injury (acute lung injury / acute respiratory distress syndrome, ALI / ARDS) refers to the body subjected to a variety of pathological stimulation of the acute inflammatory response occurs to carry out the breathing difficulty and lack of oxygen as the main clinical manifestations of respiratory failure [1]. Neonatal acute lung injury in the neonatal period is a common disease, chronic lung disease often formed on the basis of acute lung injury. Therefore, timely, appropriate diagnosis and treatment of acute lung injury, not only can improve the survival rate in children, and can reduce the incidence of chronic lung disease. We diagnosed as neonatal acute lung injury in neonatal blood platelet-activating factor (PAF), thrombomodulin (TM) for testing for neonatal lung injury and provide a theoretical basis for further study. 1 Data and methods 1.1 The diagnostic criteria are in line with ‘Practical Neonatology, 3rd edition of ‘2003 years of respiratory failure diagnostic criteria, clinical indicators: (1) difficulty in breathing: In the resting respiratory rate continued to amp;quot;60 times / min, or respiratoryamp;quot; 30 times / min, breathing rhythm changes and even apnea, 3 concave obvious sign, accompanied by moaning; (2) cyanosis: except the peripheral, and other causes cyanosis; (3) altered mental status: the spirit of apathetic response is poor, low muscle tone; (4 ) Cycle changes: cold extremities, skin capillary filling time extended (heelamp;gt; 4s), heart rate, amp;quot;100 times / min. Blood gas indicators: (1) Ⅰ respiratory failure: PaO2 ≤ 6.67kPa (50mmHg); (2) Ⅱ respiratory failure: PaO2 ≤ 6.67kPa (50mmHg), PaCO2 ≥ 9.33 kPa (70mmHg). 1.2 General Information 1.2.1 the control group (A group) randomly selected November 1, 2003 ~ November 1, 2004 in Hebei Children’s Hospital of Obstetrics