Nephrotic syndrome associated with thyroid dysfunction in clinical observation.doc

 PAGE \* MERGEFORMAT 8 Nephrotic syndrome associated with thyroid dysfunction in clinical observation [Abstract] [Objective] The primary nephrotic syndrome (PNS associated with thyroid dysfunction, the mechanism and the application of the effect of levothyroxine treatment. [Method] 59 patients with PNS in patients with thyroid dysfunction, were given strong pine 1mg/kg/d, lipid-lowering, anticoagulant, calcium and other conventional therapy, were randomly divided into 2 groups, plus levothyroxine for thyroid hormone treatment group (33 cases, not for the addition of L-thyroxine conventional therapy group (26 cases. thyroid function before and after treatment were observed (TT3, TT4, FT3, FT4 and TSH levels, urine protein negative conversion time. [Results] PNS were associated with thyroid dysfunction, TT3, TT4, FT3, FT4 levels reduced in varying degrees, and TT3 and FT3 decreased more significantly (P lt;0.01, above the index increased after treatment (P lt;0.05, before and after treatment TSH levels were at normal levels. thyroxine treatment of urinary protein negative conversion time was less than the conventional therapy group (P lt;0.05. [Conclusion] PNS of patients with thyroid dysfunction on the basis of conventional therapy plus L-thyroxine, urinary protein negative conversion conducive to shorten the course. [Keywords:] nephrotic syndrome, hypothyroidism, treatment Nephrotic syndrome (PNS often in combination in patients with the problem of low thyroid function, which not only increase the renal disease itself, but also affect the PNS in the treatment and prognosis. In this paper, 59 cases of PNS in patients with thyroid dysfunction were randomly divided into 2 groups in which a group on the basis of conventional therapy plus L-thyroxine, and achieved a certain effect, are as follows. 1 Subjects and methods 1.1 study Choose from March 2003 to June 2009 in our hospital diagnosed as PNS in patients with thyroid dysfunction, 59 patients w