Nephrotic syndrome 2 cases of arterial thrombosis.doc

 PAGE \* MERGEFORMAT 6 Nephrotic syndrome 2 cases of arterial thrombosis [Keywords:] Nephrotic syndrome; thrombosis; artery Patients with nephrotic syndrome due to a variety of factors likely combined thrombosis, venous thrombosis are more complicated, see [1], but less complicated with arterial thrombosis [2]. 2008-2009, admitted to two cases of nephrotic syndrome and lower extremity arterial thrombosis, these are as follows. A clinical data Case 1: Male, 48 years old, because ‘the right lower limb pain and swelling associated with difficulty walking in January’ admitted to hospital. 8 years ago, diagnosed as ‘Nephrotic syndrome’, long-term oral prednisone or treatment of dipyridamole and so on. Examination: facial edema, swelling beyond the middle of the right leg, the pressure of the depressed, mainly located in the dorsal foot and calf, dorsal foot can be seen at about 3 cm * 4 cm black necrotic skin lesion, plantar seen about 3 cm * 6 cm-sized blisters, dorsum beyond 2 / 3 part of the skin, cyanosis, cold, loss of sensation, toe black, dorsum and the posterior tibial artery pulse can not be palpable, palpable popliteal artery pulsation. Auxiliary examination: Vascular Doppler showed pairs of lower extremity deep venous blood flow, blood vessel digital subtraction angiography (DSA) revealed a right anterior tibial artery and peroneal artery occlusion, the posterior tibial artery distal occlusion, proximal vascular smooth lumen without stenosis; white blood cell (WBC) 22.03 * 109 / L, platelet (PLT) 542.0 * 109 / L, albumin (ALB) 16.80 g / L, fibrinogen (FIB) 7.39 g / L, thrombin time (TT) 22.9 s, urine protein. Across hospital right leg amputation, intraoperative see the hardening of the arteries, no pulse, there are reflected in its old cut artery thrombosis, arterial wall is soft, smooth lining. Pathological examination showed the right lower extremity arterial thrombosis, and machine-oriented. Case 2: Male, 24 years old, a result of ‘left foot c