Neovascular glaucoma status of the formation mechanism and treatment.doc

 PAGE \* MERGEFORMAT 26 Neovascular glaucoma status of the formation mechanism and treatment [Abstract] neovascular glaucoma (NVG) is a refractory intractable glaucoma, early diagnosis, effective treatment is to control the intraocular pressure and retain the key to better vision. But has not yet found the pathogenesis and effective treatment. This article based on recent literature on neovascular glaucoma in the pathogenesis and treatment status were reviewed. [Keywords:] neovascular glaucoma; mechanism; therapy Neovascular glaucoma (neovascular glaucoma, NVG) is a destructive intensity, the high rate of eye blind. As proliferation of fibrovascular tissue in the anterior chamber angle, leading to trabecular meshwork obstruction, and peripheral anterior synechia of iris and sexual angle Close, and then increased intraocular pressure, this elevation of intraocular pressure is often difficult to control and consequent blindness. but its precise mechanism is still unclear, it appears on the pathological state of retinal neovascularization There are several theories [1 ]: (1) hypoxia doctrine; (2) inflammation hypothesis; (3) leukocytes doctrine; (4), corneal neovascularization inhibitor destruction; (5) corneal angiogenesis factor production; (6) the elimination of corneal edema of the mechanical barrier damage; (7) the role of extracellular matrix; (8) cytokine balance theory. In recent years, studies have shown that extensive retinal ischemia is the most common cause of NVG, the formation of retinal capillary occlusion without perfusion, resulting in retinal ischemia, hypoxia, can produce new blood vessels RNV [2]. capillaries, avascular area is larger, the more prone to RNV. RNV is generally believed that the production of human tissue is a response to hypoxia. Retinal neovascularization (retinal neovascularization, RNV) is generally believed that the production will need to meet three conditions: (1) the existence of retinal biopsy; (2) retinal tis