Neural stem cell transplantation and its application in the treatment of ischemic stroke application.doc

 PAGE \* MERGEFORMAT 25 Neural stem cell transplantation and its application in the treatment of ischemic stroke application [Abstract] neural stem cells (neural stem cells, NSCs) as a self-renewal and differentiation into neurons, astrocytes, oligodendrocytes potential of neural progenitor cells, has a broad clinical application. Through migration from the structure and function of the repair, improvement of neurological diseases. In this paper, characteristics of neural stem cell biology, transplantation in the treatment of the status quo and in the treatment of ischemic stroke overview of the application to make. [Keywords:] neural stem cell; transplantation; ischemic stroke [Abstract] Neural stem cells (NSCs) are the self  renewing, multipotent cells that generate neurons, astrocytes, and oligodendrocytes in the nervous system and have a extentive perspective in clinic.Through transplantation can amelioration nervous system disease in tissue and function.In this paper, the biological charater, the transplantation current situation and the application in infarction of the neural stem cells were reviewed. [Keywords:] neural stem cells; transplantation; ischemic cerelral infarction At present, the nervous system, refractory diseases, including degenerative diseases, stroke and many other after-effects of a large number of neuron loss, nervous system can not generate new neurons, and the establishment of new synaptic connections, resulting in central nervous system structure and function after injury is difficult recovery. Since the 20th century, 90 years, successively from the mammalian neural stem cells and human central nervous system after the success of isolation and culture, ‘central nervous system after injury of non-renewable’ traditional concept was broken, with the pairs of in-depth study of neural stem cells, neural stem cells can differentiate into neurons and promotes brain structure and function of the recovery, through the neural s