Neurobiological Mechanisms of motion sickness.doc

 PAGE \* MERGEFORMAT 21 Neurobiological Mechanisms of motion sickness Motion sickness (motion sickness, MS), including navigation motion sickness (seasick), motion sickness, air sickness, space motion sickness and simulator sickness, etc. 〔 1〕 . More than a century, the mechanism of the occurrence of MS had undertaken extensive research and put forward a variety of theories, such as sensory and neural mismatch theory of conflict; neurotransmitter hypothesis; body fluids, the transfer of doctrine; hemodynamic changes in doctrine; neurotoxicity hypothesis; Otolith weight loss hypothesis and so on. However, MS occurs Neurobiological Mechanisms have not yet been fully clarified, in-depth study Neurobiological Mechanisms of MS occur, especially in the vestibular pathways and their role in neurotransmitter and receptor in order to further the prevention and treatment of MS to provide theoretical basis. Neurobiological Mechanisms of motion sickness is right research are summarized below. A motor stimulation of peripheral receptors Motor stimulation of peripheral receptors include the vestibular organs and proprioceptive receptors, which directly sense the location information passed to the vestibular nucleus (vestibular nucleus, VN), which will proprioceptive information on the one hand by the proprioceptive pathway, conduction to the cerebral cortex somatic sensory area, on the other hand by the spinocerebellar projection and projection of the incoming vestibular cerebellum and spinal cord VN, control and regulate the body’s balance, muscle tension and voluntary movement. Transport of passengers in the human body when the muscles and joints due to the location of small changes, so the contribution of proprioception to the motion sickness smaller, but for car drivers, sailors, pilots and so on in the sports wide range of activities carried out under the state personnel, proprioception the occurrence of motion sickness may play some role in support. In recent years,