Neurons in the visual pathway of Diabetes Research lesions.doc

 PAGE \* MERGEFORMAT 14 Neurons in the visual pathway of Diabetes Research lesions [Abstract] Diabetes is a serious eye complications can cause chronic metabolic diseases. Recent studies found: early diabetic microvascular disease in the retina before, appeared as the road structure and function of neuronal abnormality. Therefore, lead to diabetes visual disturbance in patients with the reason lies not only in retinal microvascular disease, but also as the way many parts of the nervous system dysfunction. We will, clinical observations, visual function and morphological research in the field of neurons in the visual pathway of diabetic disease we reviewed. [Keywords:] diabetes, visual pathway, neurons Abstract Diabetes is a chronic metabolic disease which can cause serious ocular complications. Recent findings indicated that in the early stage of diabetes, before the appearance of retinal capillary pathological changes, abnormal changes in neuronal structure and function in visual pathway have occurred. So the diabetic visual malfunction not only result from retinal capillary pathological changes, but also be related with the malfunction of neurons in many parts of visual pathway. This review will give latest findings about pathological changes of neurons in diabetic visual pathway from the aspects of clinic observation, visual function examine and histomorphology researches. ?r KEYWORDS: diabetes; visual pathway; neurons 0 Introduction Ocular complications of diabetes is the leading cause of blindness in the world one. Visual disturbance caused by diabetes, the most common causes of diabetic retinopathy (diabetic retinopathy, DR and diabetic cataracts. But there are some clinical diabetes , the eye examination and fundus fluorescein angiography (fundus fluorescence angiography, FFA and other objective findings is not sufficient to explain the degree of visual function. there are many patients with retinal microvascular disease in