Nifedipine gastrointestinal reaction induced by elimination of erythromycin in children 63 Patients.doc

 PAGE \* MERGEFORMAT 6 Nifedipine gastrointestinal reaction induced by elimination of erythromycin in children 63 Patients [Abstract] Objective To study the efficacy of nifedipine gastrointestinal reactions to eliminate. METHODS 127 patients hospitalized or live in children observation room intravenous erythromycin, nifedipine treatment group were randomly divided into 63 cases, 64 cases of non-nifedipine treated group, only intravenous erythromycin, without nifedipine treatment, the incidence of gastrointestinal reactions were compared. Results nifedipine group than in non-gastrointestinal side effects nifedipine group were significantly less than the control group, the difference was statistically significant (P lt;0 01. Conclusion nifedipine can reduce the incidence of gastrointestinal reactions induced by erythromycin. [Keywords:] nifedipine, erythromycin, erythromycin is gastrointestinal clinical response to antibiotics commonly used one. Because often accompanied by gastrointestinal reactions as to make limited use of erythromycin. The group in March 2009 to August 2009 while in the oral treatment with erythromycin or sublingual nifedipine reduced gastrointestinal side effects, are as follows. 1 Clinical data 1 1 object 127 cases were hospitalized or live observation room from intravenous erythromycin in children. Randomly assigned to nifedipine treatment group (treatment group and non-nifedipine group (the control group. Treatment of 63 cases, male 40 patients, 23 females, 4 years 40 patientsgt; 4 years old in 23 cases. the control group 64 patients, 34 males and 30 females, 4 years old in 43 cases,gt; 4 years old in 21 cases. two diseases are mostly respiratory tract infection, 92.3% in treatment group and control group accounted for 80.6% (2 = 2 49, Pgt; 0 05, the difference was not statistically significant, and comparable. In addition, patients in both groups are not accompanied by abdominal pain, diarrhea nausea, vomiting and other