Ning thirsty sugar in type 2 diabetic rats with glucose metabolism and lipid metabolism.doc

 PAGE \* MERGEFORMAT 9 Ning thirsty sugar in type 2 diabetic rats with glucose metabolism and lipid metabolism On: Sun Xuedong, Liu Chunyan, Chen Niu Yan, Hong Ying [Abstract] Objective To observe rather thirsty sugar in type 2 diabetic rats glucose metabolism and lipid metabolism. Methods of high calorie diet and low dose intraperitoneal injection of streptozotocin the method, the type 2 diabetic rat model. Will be made successful model rats were randomly divided into 50 rather thirsty sugar low, medium and high dose group 3, metformin group (Mfm) and model control group, continuous administration of 6 weeks, a separate 10 normal rats served as normal controls group. The results of sugar can significantly reduce rather thirsty type 2 diabetic rats, fasting blood glucose levels (FPG), serum free fatty acid suppression (FFA) production, reduced serum malondialdehyde (MDA) levels, elevated serum levels of high density lipoprotein cholesterol (HDL-C) levels and superoxide dismutase (SOD) activity. sugar thirsty Ning group and Mfm group, the index was no significant difference (Pgt; 0.05). conclusions might be rather thirsty sugar treat type 2 diabetes candidate drugs. [Keywords:] Type 2 diabetes, sugar, thirsty Ning, metformin, glucose metabolism, lipid metabolism, rats Abstract: Objective To study the therapeutical effect of Tangkening on rats with diabetes mellitus. Methods Successful rats with diabetes mellitus were induced by intraperitoneal injection of streptozotcin (30 mg / kg body weight) given to SD rats after feeding with high lipid forage for a month . Fifty rats with diabetes were randomly divided into five groups, three Tangkening therapy groups, Metformin therapy group, and control group. The levels of FPG, HDL-C, LDL-C, FFA, SOD and MDA were detected after six weeks. Results The serum levels of FPG, MDA, FFA, LDL-C of the Tangkening group was significantly decreased than control group, while the serum levels of SOD and HDL-C was increase