Nuclear receptor in Kidney expression of regulatory factors were.doc

 PAGE \* MERGEFORMAT 10 Nuclear receptor in Kidney expression of regulatory factors were Study: Young people and Zhang Lei Cheng Teng Jing Cai lights Abstract Objective To detect the serum containing cultured human breast cancer cells in the nuclear receptor coactivator (steroid receptor coactivator 1, SRC 1) and nuclear receptor co-suppression factor (nuclear receptor corepressor, NCOR) mRNA, the molecular level of nuclear receptor co in Kidney regulatory factor expression. Methods Wistar rats were randomly divided into three major groups, each group was further divided a large group of male and female 2, respectively, each with a large group of epimedium, Ligustrum lucidum, distilled water 14 d, preparation containing serum and serum containing culture Lack of estrogen receptor in breast cancer cells MDA MB 231, using real time quantitative RT PCR method for detection of SRC 1 and NCOR of mRNA expression. The results of kidney yang Epimedium serum of male rats raised with the expression of SRC 1, no significant effect on the NCOR; and reduced kidney yin Chinese Ligustrum coactivator SRC 1 expression, increased expression of the NCOR . JOURNAL OF TRADITIONAL CHINESE Epimedium, Ligustrum lucidum were regulators of nuclear receptor regulation of the expression. Keywords: nuclear receptor coactivator; nuclear receptor co-suppression factor; Epimedium; Ligustrum lucidum Abstract Objective To explore the effect of different tonifying kidney on expressions of steroid receptor coactivator 1 (SRC 1) and nuclear receptor repressor (NCOR) mRNA. Methods Wistar rats were divided into 3 groups and each group was divided into male and female subgroups . Wistar rats were intragastric administration with epimedium, fructus ligustri lucidi and distilled water for 14 days to make drug serum. Human breast carcinoma cell (MDA MB 231) was cultured with drug serum and the expressions of SRC 1 and NCOR mRNA were detected. Results Tonifying kidney yang Chinese medicine